Tag: bioequivalence

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Why Some People React Differently to Generic Medications

Generic medications save billions, but not everyone reacts the same. For drugs with narrow therapeutic indices like levothyroxine and warfarin, small differences in absorption can cause serious side effects. Here’s why some people feel worse after switching-and what to do about it.

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Combination NTI Drugs and Generic Availability: Coverage and Gaps

Combination NTI drugs offer precise treatment for complex conditions but face major gaps in generic availability due to bioequivalence challenges. Patients risk therapeutic failure or toxicity when generics are substituted, with no FDA-approved fixed-dose NTI combinations currently on the U.S. market.

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